Free Toxicology Resources
December 11, 2017 No CommentsToxicology
Kelly Coleman (PhD, DABT, RAC) is a: Board Certified Toxicologist, Adjunct Assistant Professor of Toxicology at the University of Minnesota, Bakken Fellow, European Registered Toxicologist, and is employed as the “Distinguished Toxicologist Technical Fellow” at Medtronic. Recently he shared with me a directory he developed of free Toxicology resources. Kelly said ––
“Dave, attached is a copy of a list of free toxicology databases that I’ve put together over the years. The biggest problem being a toxicologist is finding good tox data on chemicals, that’s why I put the list together. I hope your SafetyAwakenings.com visitors can benefit from it.”
Primary Sources
- National Library of Medicine’s TOXNET
- International Programme on Chemical Safety main search site (IPCS)
- Agency for Toxic Substances and Disease Registry (ATSDR)
- Screening Information Data Sets (SIDS)
- Environmental Health Criteria Monographs (EHC)
- OECD Existing Chemicals Database (source of new SIDS profiles)
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Secondary Sources
- Concise International Chemical Assessment Document (CICADS)
- Minimal Risk Levels (MRLs)
- Risk Assessment Information System (RAIS)
- International Toxicity Estimates for Risk Assessment (ITER)
- Risk Information Exchange (RiskIE)
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Chemistry Data
- CDC’s ppm to mg/m3 conversion calculator
- ChemSpider
- Common Chemistry (CAS numbers)
- European Chemicals Agency (ECHA)
- NIST Chemistry Web Book
- PubChem
- Wolfram Alpha
Cancer Data
- California Proposition 65 (CA Prop 65)
- Carcinogenic Potency Database (CPDB)
- International Agency for Research on Cancer Monographs (IARC)
Environmental & Occupational
- National Library of Medicine Haz Map
- NIEHS CEBS (Chemical Effects and Biological Systems)
- Registry of Toxic Effects of Chemical Substances (RTECS®) (subscription-based)
- National Institute for Occupational Safety and Health Data Base (NIOSHTIC-2)
- NIOSH Pocket Guide to Chemical Hazards (NPG)
- International Chemical Safety Cards (ICSCs)
- NTP Health Assessment and Translation
- OSHA Permissible Exposure Limits (PELs)
EPA Databases
- EPA’s Integrated Risk Information System (IRIS)
- EPA’s ChemView
- EPA’s Toxicity Reference Database (ToxRefDB)
- EPA’s Toxicity Data Warehouse (ACToR)
- EPA’s EcoTox
- Exposure Factors Handbook 2011 Edition (Final)1
FDA Databases
- FDA’s List of Color Additives for Foods, Drugs, Cosmetics, and Medical Devices
- FDA’s List of Indirect Food Contact Additives
- FDA’s List of Direct Food Additives
- FDA’s Everything Added to Food in the United States (EAFUS)
- FDA’s Inactive Drug Ingredients
- FDA’s Active Drug Ingredients
Food & Cosmetics
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In Silico Prediction Tools
- CAESER (descriptor-based models that predict REACH tox endpoints)
- OECD QSAR Toolbox (uses structures to categorize chemicals and predict endpoints)
- Tox Match (estimates skin irritation and sensitization based on structural similarity)
- Tox Tree (estimates toxic hazard by applying a decision tree approach)
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Literature Search
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Pharmaceuticals & Biologics
Reproductive Toxins
- California Proposition 65 (CA Prop 65)
Tox Profiles
- REACH Registered Substances (free tox profiles on 11,000 chemicals)
- NSF International Profiles ($25 each)
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Tox Reference Books
- Patty’s Toxicology (online version often available from corporate and university libraries)
- Sax’s Dangerous Properties of Industrial Materials (online version often available from corporate and university libraries)
- Report of the Task Group on Reference Man (great source of chemical body burden data)
Toxicology Terms
Other Useful Sites
- The EXtension TOXicology NETwork
- European Centre for Ecotoxicology and Toxicology (reports on chemicals)
- U.S. Federal Register
- Occupational Toxicology
- Federal Register (publishes notices regarding acceptable limits of chemicals)
- Globally Harmonized System of Classification and Labelling of Chemicals (GHS)1
- Information Resources in Toxicology ($175 – contains many useful links)
1 Provided by Chuck Schwartz, Ph.D., DABT, TOXDOC1
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